Author:
Chubinidze Ketevan,Kurasbediani Mariam,Doreulee Nanuli,Partsvania Besarion,Petriashvili Gia
Abstract
The combination of imaging and therapeutic agents with drug nanocarriers has received great attention due to the number of outstanding applications in nanobiology and nanomedicine. In this respect, the traditional and biocompatible magnetic nanoparticles, such as Fe3O4, play a pivotal role, having a versatile potential in imaging diagnostics, treatments and targeting in drug-delivery systems. In this work, we report on Fe3O4 nanoparticles functionalized with quercetin molecules and show that the conjugation between Fe3O4 nanoparticles and quercetin significantly modifies the fluorescent properties of the nanocomposite. The obtained results offer a reliable tool for image-assisted drug-delivery systems, targeting and penetrating such a delicate area of the human body as a blood-brain barrier.
Publisher
Institute of Metals and Technology
Subject
Metals and Alloys,Polymers and Plastics
Cited by
1 articles.
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