Paediatric Neck Lumps I – Inflammatory and Neoplastic Lesions Including Salivary Gland Abnormalities

Abstract

This article will concentrate on solid neck masses in children, giving an overview of 3 main areas: cervical lymphadenopathy, neoplasms presenting as neck masses and salivary gland abnormalities in children. Most neck lumps in children are benign, even solid masses and the child's age is an important factor in narrowing the differential diagnosis. Inflammatory lesions are very common, especially in young children and usually involve lymph nodes, but infected congenital cystic lesions can mimic inflammatory processes. The most common inflammatory masses are reactive or suppurative lymphadenitis, which classically present following an upper respiratory tract or pharyngeal infection. Malignant lesions are seen occasionally and it is important to know when to be concerned about a child's neck mass. Malignant lesions tend to be painless, solid and associated with systemic manifestations. Ultrasound is the primary imaging modality of choice for children, but does have limitations. It is vital that all imaging is interpreted in conjunction with clinical information, especially as imaging findings can be non-specific. Any lesion that does not have typical benign appearances or behaviour requires biopsy. Salivary gland disorders are uncommon in children compared with adults; salivary calculi, autoimmune disorders and tumours are rare. The most frequent cause of parotid swelling in a child is infection, usually viral, although intra-parotid lymph nodes can suppurate resulting in abscess formation. As with neck masses in other locations, certain factors in the clinical history should raise the possibility of malignancy and prompt further investigation, including biopsy. These include rapid growth, facial nerve palsy and associated lymphadenopathy.