Abstract
The goal is to study the indicators of somatotropic hormone and insulin-like growth factor-1 to assess the effect on anthropometric indicators of children with type 1 diabetes mellitus. 74 children with type 1 diabetes mellitus and 14 children in the control group were examined. Average age 12±3.5 years. The assessment of physical development was carried out on the basis of an assessment of anthropometric indicators — height and body weight with the calculation of BMI and compared with centile tables. Determination of the concentration of hormones such as GH and IGF-1 was determined by special ELISA kits using the enzyme immunoassay method using an analyzer (Mindray MR-96A). The obtained data were subjected to statistical processing. It was revealed that 8 (36.4%) boys and the majority of girls 14 (63.6%) achieved the target level of glycated hemoglobin. Children with T1DM are statistically significant and stunted in height and weight compared to healthy children in the control group.
Publisher
Publishing Center Science and Practice
Reference6 articles.
1. Uvaidillaeva, F. T., & Tukhvatshin, R. R. (2023). Vliyanie gormona rosta na etiopatogeneticheskie i klinicheskie osobennosti razvitiya sakharnogo diabeta 1 tipa u detei (obzor literatury). Vestnik KRSU, 23(9), 131-135. https://doi.org/10.36979/1694-500X-2023-23-9-131-135
2. Shaikh, W., Riaz, M., Askari, S., & Basit, A. (2022). Linear Growth and Final Height in People With Type 1 Diabetes: A Study From Karachi, Pakistan. Cureus, 14(2). https://doi.org/10.7759/cureus.22397
3. Hovsepian, S., Chegini, R., Alinia, T., Ghaheh, H. S., Nouri, R., & Hashemipour, M. (2024). Final height in children and adolescents with type 1 diabetes mellitus: A systematic review and meta-analysis. Hormones, 23(1), 35-48. https://doi.org/10.1007/s42000-023-00500-3
4. Department of Health and Human Services, Centers for Disease Control and Prevention. Developed by the National Center for Health Statistics in collaboration with the National Center for Chronic Disease Prevention and Health Promotion. 2000.
5. Parthasarathy, L., Khadilkar, V., Chiplonkar, S., & Khadilkar, A. (2016). Longitudinal growth in children and adolescents with type 1 diabetes. Indian pediatrics, 53, 990-992. https://doi.org/10.1007/s13312-016-0974-1