A clinical case of pityriasis rubra pilaris - juvenile type
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Published:2023-06-28
Issue:3
Volume:20
Page:115-118
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ISSN:1812-2892
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Container-title:Journal of Clinical Medicine of Kazakhstan
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language:
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Short-container-title:J CLIN MED KAZ
Author:
Mukhamedov Bahrambek1ORCID, Koldarova Evelina2ORCID, Kurbanov Obid1ORCID
Affiliation:
1. Department of Therapeutic Subjects, Tashkent State Dental Institute, Tashkent, Uzbekistan 2. Dermatology Department, Asmo clinic, Tashkent, Uzbekistan
Abstract
Pityriasis rubra pilaris is a rare chronic inflammatory papulo-squamous skin disease, the pathogenesis of which is still unclear. The pathological essence of the disease is associated with a violation of keratinization against the background of hyperactivity of keratinocytes with subsequent inflammation, as well as with vitamin A dysmetabolism and a weakening of the protein-binding fiction of the liver. Unfortunately, treatment is complex with inconsistent improvement from topical therapies, including emollients, keratolytics, corticosteroids, vitamin D analogs, and retinoids. We present a clinical case of the juvenile type of Devergie’s disease in a 3-year-old child, which was caused by poisoning.
Publisher
JSC National Scientific Medical Research Center
Reference22 articles.
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