Affiliation:
1. Department of Genetic Engineering, School of Bioengineering, SRM Institute of Science and
Technology, Kattankulathur, India
Abstract
X Chromosome is the sex chromosome that is found in many organisms.
Both males and females, including mammalians, have X Chromosomes. Females have
XX sets of chromosomes, and males have XY sets of chromosomes. X Chromosome
aids in identifying the sex of the organism. The Human X chromosome contains
approximately 1500 genes. These genes may undergo some genetic alterations and
eventually lead to complex diseases. Genetic mutations in some of the genes of the X
chromosome are associated with cancer. Some specific mutations are observed in
human cancer cells. This chapter specifically relayed on X chromosomal genes that are
associated with different types of cancer and gave information on the location of the
gene in the X chromosome. Moreover, the function of the specific gene and
information regarding how many types of cancers were associated with a particular
gene, has also been provided.
Publisher
BENTHAM SCIENCE PUBLISHERS