The Story of Diabetes and its Causes

Abstract

Diabetes mellitus (DM) is a complex metabolic disorder whose rising prevalence is terrible. A deeper knowledge of the pathophysiology of diabetes could assist in discovering possible therapeutic targets for treating diabetes and its associated problems. The common feature of diabetes, regardless of the specific pathology involved, is hyperglycemia brought on by the death or dysfunction of β-cell. As insulin deficiency gets worse over time, dysglycemia progresses in a continuum. This chapter has provided a brief review of the pathophysiology of diabetes. Also, the roles of genetics and environmental factors have been emphasized.