Affiliation:
1. Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran
Abstract
The preparation of medicinally promising spiro1,4–dihydropyridines accompanied by their
applications in biological and pharmaceutical activities is presented. Spiro1,4–dihydropyridines were
synthesized using numerous reported methods including bronested acids such as p-TSA, AcOH, nano-ranged
calix[4]arene tetracarboxylic acid, sulfamic acid, PEG-OSO3H, tetramethylguanidinium triflate; lewis acids
including Zn(OTf)2, FeCl3, copper, alum, aluminosilicate nanoparticles, MnFe2O4 nanoparticles, manganese
ferrite nanoparticles, BF3OEt2; under alkaline conditions such as Et3N and piperidine; ionic liquids such as
[KAl(SO4)2·12H2O] and [Bmim]PF6, [MIM(CH2)4SO3H][HSO4]; and other miscellaneous procedures, for
example, microwave-assisted catalyst and solvent-free conditions, using iodine, PEG-400, and NaCl.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
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