Affiliation:
1. State Key Laboratory of Crop Biology, Shandong Key Laboratory of Crop Biology, Shandong Agricultural University, Tai'an 271018, China
Abstract
Background:
The quality of Traditional Chinese Medicine (TCM), reflected by its bioactive
compounds and associated contents, is directly linked to its clinical efficacy. Therefore, it is of great
importance to improve the quality of TCM by increasing the bioactive compound content.
Methods:
Mapping the active component content-associated QTLs in TCM and further marker-assisted breeding
have enabled us to rapidly and effectively cultivate new varieties with high bioactive compound contents, which has
opened the door for genetic breeding studies on medicinal plants.
Results:
In this paper, a strategy and technical molecular breeding method for TCM are discussed. The development
of, four methods of and progress in functional marker development as well as the applications of such markers in
TCM are reviewed.
Conclusion:
The progress in, challenges of, and future of marker-assisted breeding for quality improvement of TCM
are discussed, which provide valuable scientific references for future molecular breeding.
Funder
Key Research and Development Plan of Shandong Province
Natural Science Foundation of Shandong Province of China
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biotechnology
Cited by
4 articles.
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