Roles of Gut Microbiota in Colorectal Carcinogenesis Providing a Perspective for Early Diagnosis and Treatment-Reference-Cited by-同舟云学术

Roles of Gut Microbiota in Colorectal Carcinogenesis Providing a Perspective for Early Diagnosis and Treatment

Published:2022-11 Issue:13 Volume:23 Page:1569-1580
ISSN:1389-2010
Container-title:Current Pharmaceutical Biotechnology
language:en
Short-container-title:CPB

Author:

Rezaee Mohammad Ahangarzadeh¹²³,Nouri Roghayeh⁴¹,Hasani Alka¹²,Asgharzadeh Mohammad⁵,Sefidan Fatemeh Yeganeh¹,Hemmati Fatemeh¹

Affiliation:

1. Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2. Department of Medical Microbiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

3. Clinical Research Development Unit of Children Educational, Research and Treatment Center, Tabriz University of Medical Sciences, Tabriz, Iran

4. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

5. Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Abstract

Abstract: Colorectal cancer (CRC) is the third most prevalent malignant neoplasm in the world. CRC is influenced by both environmental and genetic factors. Through toxin-mediated DNA damage and the promotion of persistent dysregulated inflammation, the gut microbiota plays a crucial role in the development of CRC. In this review, we discussed the correlation between the bacterial microbiota and CRC carcinogenesis as well as the mechanism by which Streptococcus bovis/gallolyticus, Fusobacterium nucleatum, Bacteroides fragilis, and Escherichia coli can cause CRC.

Funder

Tabriz University of Medical Sciences, Tabriz, Iran

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Biotechnology

Reference119 articles.

1. Saus E.; Iraola-Guzmán S.; Willis J.R.; Brunet-Vega A.; Gabaldón T.; Microbiome and colorectal cancer: Roles in carcinogenesis and clinical potential. Mol Aspects Med 2019,69,93-106

2. Bundgaard-Nielsen C.; Baandrup U.T.; Nielsen L.P.; Sørensen S.; The presence of bacteria varies between colorectal adenocarcinomas, precursor lesions and non-malignant tissue. BMC Cancer 2019,19(1),399

3. Al-Sohaily S.; Biankin A.; Leong R.; Kohonen-Corish M.; Warusavitarne J.; Molecular pathways in colorectal cancer. J Gastroenterol Hepatol 2012,27(9),1423-1431

4. Vivarelli S.; Salemi R.; Candido S.; Falzone L.; Santagati M.; Stefani S.; Torino F.; Banna G.L.; Tonini G.; Libra M.; Gut microbiota and cancer: From pathogenesis to therapy. Cancers (Basel) 2019,11(1),38

5. Koliarakis I.; Messaritakis I.; Nikolouzakis T.K.; Hamilos G.; Souglakos J.; Tsiaoussis J.; Oral bacteria and intestinal dysbiosis in colo-rectal cancer. Int J Mol Sci 2019,20(17),4146

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. COVID-19, Long COVID, and Gastrointestinal Neoplasms: Exploring the Impact of Gut Microbiota and Oncogenic Interactions;Archives of Cancer Science and Therapy;2024-09-04

2. Modulation of the intestinal microbiota as a new strategy for the prevention and treatment of comorbid chronic cardiovascular diseases and colorectal cancer in one patient. Review;MD-Onco;2024-06-14

3. Potential Pathogens Associated with Colorectal Cancer;2023

4. Trends in the Comprehension and Management of Gastrointestinal Tract Disorders;Journal of Clinical Medicine;2022-03-21