Recent Advances in Hypervalent Iodine Reagents and m-CPBA Mediated Oxidative Transformations

Author:

Varala Ravi1ORCID,Seema Vittal2,Amanullah Mohammed3,Ramanaiah Seella4,Alam Mohammed Mujahid5

Affiliation:

1. Scrips Pharma, Mallapur, Hyderabad 500076, Telangana, India

2. Department of Chemistry, RGUKT, Basar, Mudhole 504107, Telangana, India

3. Department of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia

4. Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi 110021, India

5. Department of Chemistry, College of Science, King Khalid University, Abha, Saudi Arabia

Abstract

Abstract: Among the several peroxides available, meta-chloroperbenzoic acid (mCPBA) plays an efficient role of oxidizing reagent and is used for many oxidative transformations, such as oxidation of various functional groups, carbon-carbon, carbon-hetero bond formation, heterocyclic ring formation, heteroarylation, oxidative cross-coupling, lactonization, oxidative dearomatization, α-oxytosylation or α-acetoxylation, oxidative C-C bond activation and in other miscellaneous reactions. The purpose of this review is to critically discuss the significant contributions of mCPBA along with hypervalent iodine/iodine reagents in organic synthesis from mid-2015 to date.

Funder

Deanship of Scientific Research at King Khalid University, Saudi Arabia

Publisher

Bentham Science Publishers Ltd.

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