Affiliation:
1. School of Hospitality, Jiangsu Food and Pharmaceutical Science College, Huaian 223003, P.R. China
2. Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, P.R. China
Abstract
Abstract:
2,3-Dihydrobenzofuran and coumaranone are readily available in numerous naturally
occurring compounds. They mostly exist in plenty of food plants and medicinal plants.
Such compounds constitute a series of flavor components and bioactive molecules. Their
preparation has been an attractive field of research. In the past few decades, great efforts
have been made in the preparation of the 2,3-dihydrobenzofuran structure through both
metal-catalyzed and organocatalyzed ways. Visible light-promoted reactions sprang up in
the early 21st century and represent a green manner of transformations. Under the irradiation
of visible light, radicals could be generated under milder conditions. Thus, visible lightpromoted
reactions spread widely in the field of chemical synthesis. In recent years, visible
light-promoted preparation of 2,3-dihydrobenzofuran and coumaranone has been developed
by different groups, including both intramolecular and intermolecular reactions. The benign reaction conditions
allow better functional group-tolerance and lead to diverse structures. Several reviews on the synthesis of 2,3-
dihydrobenzofuran have been reported. However, visible light-promoted approaches to such structures have not
been well reviewed. Our review will cover the literature that has been reported on the discovery of 2,3-
dihydrobenzofuran in food and visible light-promoted preparation of 2,3-dihydrobenzofuran, attempting to
summarize the existing methods and provide guidance to the chemists on the present challenges.
Publisher
Bentham Science Publishers Ltd.