Catalytic Syntheses of Pyrano[3,2-C]Quinolone and -Quinoline Derivatives and their Potential Therapeutic Agents-Reference-Cited by-同舟云学术

Catalytic Syntheses of Pyrano[3,2-C]Quinolone and -Quinoline Derivatives and their Potential Therapeutic Agents

Published:2024-09-05 Issue: Volume:29 Page:
ISSN:1385-2728
Container-title:Current Organic Chemistry
language:en
Short-container-title:COC

Author:

Aly Ashraf A.¹^ORCID,Abd El-Naby Hisham A.¹,Ahmed Essam Kh.¹,Gedamy Sageda A.¹,Alshammari Mohammed B.²^ORCID,Ahmed Akil²,Braese Stefan³⁴^ORCID

Affiliation:

1. Chemistry Department, Faculty of Science, Minia University, 61519 El-Minia, Egypt

2. Chemistry Department, College of Sciences and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharij, Saudi Arabia

3. Institute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany

4. Institute of Biological and Chemical Systems (IBCS-FMS), Karlsruhe Institute of Technology, Ggenstein-Leopoldshafen, 76344 Karlsruhe, Germany

Abstract

Abstract: Pyrano[3,2-c]quinolone and pyrano[2,3-c]quinoline, as promising molecules, have garnered more attention due to their interesting biological properties. This review dealt with the catalytic synthesis of the former candidates in the last 20 years. Multi-component reactions (MCRs) are synthetic routes that produce a single product from three or more reactants in a one-pot step procedure. We herein reported on the advantages of catalysis in synthesizing the target compounds using the MCR sequence. We also discussed the mechanism and explained the chosen catalyst's utility in the target molecules' selectivity. Finally, this recent review focuses on the biological applications of these molecules as anticancer, antimicrobial activities, anti-diabetic, antiinflammatory, anti-Alzheimer, and antitubercular agents.

Publisher

Bentham Science Publishers Ltd.