Author:
Berjano Enrique J,Navarro Enrique,Ribera Vicente,Gorris Javier,Alió Jorge L
Abstract
This paper reviews the different applicators and electrodes employed to create localized heating in the cornea by means of the application of radiofrequency (RF) currents. Thermokeratoplasty (TKP) is probably the best known of these techniques and is based on the principle that heating corneal tissue (particularly the central part of the corneal tissue, i.e. the central stroma) causes collagen to shrink, and hence changes the corneal curvature. Firstly, we point out that TKP techniques are a complex challenge from the engineering point of view, due to the fact that it is necessary to create very localized heating in a precise location (central stroma), within a narrow temperature range (from 58 to 76ºC). Secondly, we describe the different applicator designs (i.e. RF electrodes) proposed and tested to date. This review is planned from a technical point of view, i.e. the technical developments are classified and described taking into consideration technical criteria, such as energy delivery mode (monopolar versus bipolar), thermal conditions (dry versus cooled electrodes), lesion pattern (focal versus circular lesions), and application placement (surface versus intrastromal).
Publisher
Bentham Science Publishers Ltd.
Subject
Biomedical Engineering,Medicine (miscellaneous),Bioengineering
Reference48 articles.
1. Mendez-Gutierrez A. “Review of thermokeratoplasty developments,” In: Pinelli JR, Pascucci SE, Eds. Conductive keratoplasty A primer. Thorofare: SLACK 2005; pp. 3-8.
2. Ismail MM, Pérez-Santonja JJ, Alió JL JL. “Correction of the hyperopia and hyperopic astigmatism by laser thermokeratoplasty,” In: Serdarevic ON, Ed. Refractive Surgery: Current Techniques and Management. New York: Igaku-Shoin 1997; pp. 263-74.
3. Shaw EL, Gasset AR. “Thermokeratoplasty (TKP) temperature profile,” Invest Ophthalmol 1974; 13 : 181-6.
4. Gasset AR, Kaufman HE. “Thermokeratoplasty in the treatment of keratoconus,” A J Ophthalmol 1975; 79 : 226-32.
5. Trembly BS, Hashizume N, Moodie KL, Cohen KL, Tripoli NK, Hoopes PJ. “Microwave thermal keratoplasty for myopia: keratoscopic evaluation in porcine eyes,” J Refract Surg 2001 Nov-Dec; 17 (6) : 682-8.
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献