Hyperbranched Nanostructure Drug Delivery Carrier: Dendrimer

Abstract

Abstract: Dendrimers are nanosized macromolecules with a hyperbranched globular shape that are commonly employed for drug delivery. They have shown to be both complex and valuable due to their high level of surface functioning, adaptability, and unique features. Furthermore, dendrimers have a wide range of applications in supramolecular chemistry, mainly in self-assembly processes. The potential of this macromolecule to construct a definite architectural design in terms of size, shape, branching length, density, and its well-defined molecular structure and segmented spherical construction has sparked a wide range of research on the interactions that occur between biological organisms. Dendrimers are "grown" from a central core in a repetitive divergent manufacturing process, with each succeeding step representing a new "generation" of the dendrimer. In comparison to linear polymers, dendrimers have more precisely controlled structures, globular in shape, and have a specific molecular weight rather than a range of molecular weights. The divergence in dendritic structure customization provides a one-of-a-kind framework for drug delivery to acute and chronic diseases. The development of efficient drug delivery systems based on dendrimers has attracted much interest in recent years. This review aims to discuss some important perspectives and recent patents regarding dendrimers.