Author:
Fedeli Piergiorgio,Casella Claudia,Buccelli Claudio,Cannovo Nunzia,Graziano Vincenzo
Abstract
Background:Genetic research has become an indispensable instrument for medical research, and the subjects involved have both divergent and convergent interests.Objective:The possibility of having more detailed genetic information undoubtedly offers benefits for the health of the subject, but could also pose risks and make the subject vulnerable to discrimination.Methods:The scientific community has viewed very favorably the public health utility of family history, in which data from a family whose members suffer from chronic pathologies is collected and filed, in order to develop a sort of “stratification of family risk.”Even though in the last decade the scientific and juridical literature has contributed greatly to the topic of biobanks, the perplexities that continue to surround this theme give the idea that current ethical protocols on research are inadequate.Results:Researchers, citizens, International stakeholders, mass media, Public Health and Governments play a key role in genetic research. It is obvious that the methods used for genetic research do not present intrinsic risks; they are much less dangerous than other activities of diagnosis and research. Before authorizing a research project, it is important to reflect on the responsibility and transparency of the studies to be conducted, and on the impact they may have on the interests of public health.Conclusion:We believe that the highest priority need is to develop a common language on the theme, as is the case in the sphere of clinical experimentation where rules of good clinical practice, albeit at times conflicting, have led to uniform convergences in the scientific world on the points to be actuated.
Publisher
Bentham Science Publishers Ltd.
Subject
Public Health, Environmental and Occupational Health,Community and Home Care,Health (social science)
Reference73 articles.
1. Piazza A. Le biobanche: tra genetica e diritto. Iustitia 2006; 1 : 41.
2. Cannovo N, Paternoster M, Buccelli C. Predictive genetic tests for employment purposes: why not? Med Law 2010; 29 (3) : 419-32.
3. Wang L, Fan C, Topol SE, Topol EJ, Wang Q. Mutation of MEF2A in an inherited disorder with features of coronary artery disease. Science 2003; 302 (5650) : 1578-81.
4. Savoia C, Volpe M, Grassi G, Borghi C, Agabiti Rosei E, Touyz RM. Personalized medicine-a modern approach for the diagnosis and management of hypertension. Clin Sci (Lond) 2017; 131 (22) : 2671-85.
5. Florez JC. Mining the genome for therapeutic targets. Diabetes 2017; 66 (7) : 1770-8.
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