Synthesis, β -catenin Translocation Capability and ALP Activation Activity of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives-Reference-Cited by-同舟云学术

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Synthesis, β -catenin Translocation Capability and ALP Activation Activity of 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one Derivatives

Published:2018-01-11 Issue:1 Volume:14 Page:
ISSN:1573-4064
Container-title:Medicinal Chemistry
language:en
Short-container-title:MC

Author:

Hou Shicheng¹,Xu Henan¹,Hu Jianshu²,Hou Jian¹,Wang Yan²,Jin Zhe¹,Wan David C.C.²,Hu Chun¹

Affiliation:

1. Key Laboratory of Structure-based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China

2. School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery

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1. Bicyclic 5-6 Systems With One Bridgehead (Ring Junction) Nitrogen Atom: Three Extra Heteroatoms 1:2;Comprehensive Heterocyclic Chemistry IV;2022

2. Discovery of 3-amino-4-{(3S)-3-[(2-ethoxyethoxy)methyl]piperidin-1-yl}thieno[2,3-b]pyridine-2-carboxamide (DS96432529): A potent and orally active bone anabolic agent;Bioorganic & Medicinal Chemistry Letters;2021-12

3. Synthesis and biological activities of drugs for the treatment of osteoporosis;European Journal of Medicinal Chemistry;2020-07

4. Cascade of Michael Addition/Retro‐Michael Reaction/Skeletal Rearrangement in the Synthesis of Arylmethylidene Derivatives of Imidazothiazolotriazines;ChemistrySelect;2019-09-17

5. Synthesis and structure-activity relationship of 4-alkoxy-thieno[2,3-b]pyridine derivatives as potent alkaline phosphatase enhancers for osteoporosis treatment;Bioorganic & Medicinal Chemistry Letters;2019-07

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