Affiliation:
1. Research Institute for the Chemical Industry, National Council of Scientific and Technical Research, Faculty of Engineering, National University of Salta, Salta Capital, Argentina
Abstract
Background:
Chitosan (CS) is a biomaterial derived from chitin, known for its excellent biological
properties. One of the most interesting features of CS is its potential for chemical derivatization,
which makes it a versatile material and allows to expand its applications. In the last years, the
interest on this polymer and its pharmaceutical applications has notably increased. This biopolymer is
being widely studied for its interesting properties, such as bioadhesion, antimicrobial activity, biocompatibility,
and biodegradability. Other promising properties of CS include its modulation of immunological
response, hemostasis, and wound and bone healing activity.
Objective:
In this work, a critical review is performed covering its conventional and novel applications,
specially focused on pharmaceutical area, providing a clear picture of the current state of art to serve as
a basis to direct future research in this field.
Conclusion:
Despite all the qualities of this polymer, there are only few CS-based products in the market,
so it is a priority to enhance the research to develop new technologies and CS-based systems to enforce
this biopolymer in the industry.
Funder
Consejo de Investigación de la Universidad Nacional de Salta, (CIUNSa)
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science,Biomedical Engineering
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