Research Progress of Mitophagy in Alzheimer's Disease-Reference-Cited by-同舟云学术

Research Progress of Mitophagy in Alzheimer's Disease

Published:2023-12 Issue:12 Volume:20 Page:827-844
ISSN:1567-2050
Container-title:Current Alzheimer Research
language:en
Short-container-title:CAR

Author:

Yao Jinglin¹²³^ORCID,Kan Bohong⁴²³^ORCID,Dong Zhengjia¹³^ORCID,Tang Zhenyu¹²^ORCID

Affiliation:

1. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China

2. Tianjin Institute of Acupuncture & Moxibustion, Tianjin, China

3. National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China

4. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China;

Abstract

Abstract: The prevalence of Alzheimer's disease (AD) is increasing as the elderly population, which hurts elderly people's cognition and capacity for self-care. The process of mitophagy involves the selective clearance of ageing and impaired mitochondria, which is required to preserve intracellular homeostasis and energy metabolism. Currently, it has been discovered that mitophagy abnormalities are intimately linked to the beginning and progression of AD. This article discusses the mechanism of mitophagy, abnormal mitophagy, and therapeutic effects in AD. The purpose is to offer fresh perspectives on the causes and remedies of AD.

Funder

Special Scientific Research Project of Integrated Traditional Chinese and Western Medicine of Tianjin Municipal Health Commission

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

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