Stereospecific Total Synthesis of Putaminoxin 1 by Ring Closing Metathesis and Enantioselective Epoxidation-Reference-Cited by-同舟云学术

Stereospecific Total Synthesis of Putaminoxin 1 by Ring Closing Metathesis and Enantioselective Epoxidation

Published:2023-06 Issue:2 Volume:10 Page:128-132
ISSN:2213-3372
Container-title:Current Organocatalysis
language:en
Short-container-title:COCAT

Author:

Shekhar Vanam¹^ORCID,Sudhakar Chithaluri²^ORCID,Veerareddy Nagireddy³

Affiliation:

1. Department of Chemistry, Govt. Degree College, Nakrekal, Osmania University, Telangana, 508211, India

2. Department of Chemistry, School of Science, GITAM Deemed to be University, Telangana, 502 102, India

3. Department of Chemistry, University of Hyderabad, Telangana, 500046, India

Abstract

Abstract: The stereoselective synthesis of putaminoxin 1, a biologically active natural phototoxic lactone has been synthesized from (R)-2-Propyloxirane and Hex-5-en-1-ol. The synthesis involves Jacobsen’s hydrolytic kinetic resolution and ring-closing metathesis as the key steps.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Analytical Chemistry,Catalysis

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