Affiliation:
1. Totbiopharm Shanghai R&D Center, 781 Cailun Road, Shanghai, 201203, China
Abstract
The oncolytic viruses now hold a promise of new therapeutic strategy for cancer. Its concept
has inspired a wave of commercial research and development activities for the products of this
category in China since 1998. The first commercialized oncolytic virus product in the world, Oncorine
(H101), developed by Shanghai Sunway Biotech Co., Ltd since 1999, was approved by Chinese
SFDA in November, 2005 for nasopharyngeal carcinoma in combination with chemotherapy
after the phase III clinical trial, and finally acquired GMP certificate in August, 2006. This review
introduces how Oncorine was successfully developed in China, and how the Chinese market responded
after it was launched into the market in 2006.
Publisher
Bentham Science Publishers Ltd.
Subject
Cancer Research,Drug Discovery,Pharmacology,Oncology
Cited by
200 articles.
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