Affiliation:
1. Key Laboratory for Neuro-Information of Ministry of Education, School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610054, China
Abstract
Background:The location of proteins in a cell can provide important clues to their functions in various biological processes. Thus, the application of machine learning method in the prediction of protein subcellular localization has become a hotspot in bioinformatics. As one of key organelles, the Golgi apparatus is in charge of protein storage, package, and distribution.Objective:The identification of protein location in Golgi apparatus will provide in-depth insights into their functions. Thus, the machine learning-based method of predicting protein location in Golgi apparatus has been extensively explored. The development of protein sub-Golgi apparatus localization prediction should be reviewed for providing a whole background for the fields.Method:The benchmark dataset, feature extraction, machine learning method and published results were summarized.Results:We briefly introduced the recent progresses in protein sub-Golgi apparatus localization prediction using machine learning methods and discussed their advantages and disadvantages.Conclusion:We pointed out the perspective of machine learning methods in protein sub-Golgi localization prediction.
Funder
Research program of science and technology at universities of Inner Mongolia Autonomous Region
Fundamental Research Funds for the Central Universities of China
National Nature Scientific Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Computational Mathematics,Genetics,Molecular Biology,Biochemistry
Cited by
127 articles.
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