Affiliation:
1. School of Pharmaceutical Sciences, Rajiv Gandhi Proudyogiki Vishwavidyalaya, Bhopal-462033, MP, India
Abstract
Background:
In recent times, CNTs have been much explored, and a topic of interest in
science and technology and not limited to any specific field. The diverse application area included
field emission, energy storage, atomic electronics, nuclear force microscopy, and imaging. In biology,
CNTs engaged in developing novel tools for the delivery of biologically important molecules as
well as in diverse biomedical arenas. However, despite their promise, studies of the interaction of
CNTs with biological systems most often resulted in cytotoxicity at an early stage, and problems
relevant to the safety and biological compatibility of CNTs are of greatest importance. The toxic
effects of carbon nanotubes (CNTs) are required to be either evaded, diminished, or decreased up-to
clinical acceptance level. However, rich surface chemistry that CNTs possess can be employed to
functionalize them as per the specific biomedical requirements which may be useful to overcome
toxicity issues.
Objective:
To explore the recent reports on the functionalized CNTs for a variety of biomedical applications
such as biosensing, electrochemical detection of drug, bone tissue engineering, and vitamin
detection.
Results:
Most of the cited articles reveal that the functionalization of CNTs may reduce its toxicity
and enhance its utilization in different biological applications.
Conclusion:
The review successfully frames to provide novel applications of functionalized CNTs in
the biomedical arena including detection of vitamins, bone tissue engineering, electrochemical determination
of drugs, and development of biosensors along with a discussion on current patent and
clinical trial status of functionalized CNTs.
Funder
Department of Science and Technology
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering,Biotechnology
Cited by
8 articles.
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