Type 2 Diabetes Study, Introduction and Perspective

Author:

Lu Da-Yong,Che Jin-Yu,Yarla Nagendra Sastry,Zhu Hong,Lu Ting-Ren,Xu Bin,Putta Swathi

Abstract

Background:The prevalence of Type 2 Diabetes Mellitus (T2DM) continues to rise globally. The T2DM prevalence is not only in developing countries, but also in developed countries now. Correspondingly, the therapeutics of T2DM calls for a change (higher efficiency) due to growing number of patients and increasing economic burdens globally. Entering into this millennium, both piecemeal pathways (idea driven) and exponential growth of human genomic study are developing quickly. Genetypic-phenotypic translation, modern diagnostics, pharmacology, drug developments, traditional Chinese medicine, personalized medicine and so on are promising disciplines for this change. The clinical anti-diabetic therapeutics, pathogenesis, drug development pipelines are especially highlighted.Conclusion:In summary, a general landscape and principle of T2DM is provided.

Publisher

Bentham Science Publishers Ltd.

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference46 articles.

1. Lu DY, Che JY, Yarla NS, et al. Types 2 diabetes prevention, treatments and new drug developments. Clin Immunol Endocr Metab Drugs 2018; 5.

2. Kaul K, Tarr JA, Ahmad SI, Kohner EM, Chibber R. Introduction to diabetes Mellitus. Diabetes: An Old Disease, A New Insights. In: Ahmad S, Ed. 2013; 1-11.

3. Zimmet PZ, Magliano DJ, Herman WH, Shaw JE. Diabetes: A 21st century challenge. Lancet Diabetes Endocrinol 2014; 2 (1) : 56-64.

4. Ahmad S, Ed. An Old Disease, A New Insights 2013.

5. Lu DY, Che JY, Yarla NS, et al. Diabetes prevention and treatments, a specific topic for modern medicines. J Metab Syndr 2017; 8 (3) : 231.

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