Affiliation:
1. Human Cytogenetics and Genomics Laboratory, Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam, Tamilnadu 603103, India
Abstract
Absatract:
The effectiveness, cell viability, and selective delivery of medications and diagnostic substances to target organs, tissues, and organs are typical concerns in the care and prognosis of many illnesses. Neurological diseases pose complex challenges, as cerebral targeting represents a yet unresolved challenge in pharmacotherapy, owing to the blood-brain boundary, a densely com-pacted membrane of endothelial cells that prohibits undesired chemicals from reaching the brain. Engineered nanoparticles, with dimensions ranging from 1 to 100 nm, provide intriguing biomedi-cal techniques that may allow for resolving these issues, including the ability to cross the blood-brain barrier. It has substantially explored nanoparticles in the previous century, contributing to sub-stantial progress in biomedical studies and medical procedures. Using many synthesized nanoparti-cles on the molecular level has given many potential gains in various domains of regenerative medi-cine, such as illness detection, cascaded cell treatment, tissue regeneration, medication, and gene editing. This review will encapsulate the novel developments of nanostructured components used in neurological diseases with an emphasis on the most recent discoveries and forecasts for the future of varied biological nanoparticles for tissue repair, drug inventions, and the synthesizing of the deliv-ery mechanism.
Publisher
Bentham Science Publishers Ltd.
Subject
Biomedical Engineering,Medicine (miscellaneous),Bioengineering