Nano Emulsion Drug Delivery System: A Review

Author:

Mishra Nitin1,Kaushik Niranjan1ORCID,Sharma Pramod Kumar1,Alam Md. Aftab1

Affiliation:

1. Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Gautam Budh Nagar, 201306, Uttar Pradesh, India

Abstract

Abstract: In nanoemulsions, both oil and water droplets are stabilised by an amphiphilic surfactant. Ultrafine dispersions with varying drug loading, viscoelastic properties, and aesthetic characteristics may be useful for the administration of medication. A 20-500-nanometer droplet size range for nanoemulsions has been established. The biological behavior of a nanoemulsions formulation is heavily influenced by its droplet diameter and surface properties. Small droplet size results in clear emulsions; therefore, the appearance of the product is unaffected even by the addition of an oil phase. Nanoemulsions are oil-in-water dispersions that are transparent or translucent and are stabi-lized by an interfacial layer of surfactants and cosurfactant particles with droplet size smaller than 100 nm. New nanoscience-based technologies are becoming increasingly popular as a means of im-proving food safety, quality, and nutrition. In this field, nanoemulsions have been a key focus since they can be readily manufactured using current food components and technology. Food nanoemul-sions, which are tiny oil droplets distributed in water, are being used as delivery methods for a vari-ety of hydrophobic compounds, including nutrients, nutraceuticals, antioxidants, and antimicrobial agents. The present review is focused on the formulation, characterization, and applications of nanoemulsions.

Publisher

Bentham Science Publishers Ltd.

Subject

Biomedical Engineering,Medicine (miscellaneous),Bioengineering

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