Affiliation:
1. Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, India
Abstract
Background:
Toxoplasmosis is a common worldwide zoonotic infection affecting warm
blooded animals and humans caused by Toxoplasma gondii. Clinical features range from mildfebrile
illness and lymphadenopathy in the immunocompetent host to encephalitisin the immunosuppressed
host (E.g. HIV infected patients). Congenital infection can also occur. For effective control and treatment
of toxoplasmosis, accurate detection of T. gondii infection is important.
Objective:
In this study, ELISA detecting anti-toxoplasma antibodies IgM and IgG has been used for
diagnosing Toxoplasmosis in patients.
Methods:
Enzyme-linked immunosorbentassay (ELISA) was carried out in serum samples collected
from 40 patients to detect anti-toxoplasma IgG and IgM antibodies as a part of work up in suspected
cases. Relevant clinical history was also taken.
Result:
Of the total 40 samples taken, only one sample came positive for IgM and 9 came positive for
IgG antibody. All patients who were seropositivefor T. gondii antibodies had HIV infection. Five patients
were in the age group between 30 to 40 years.
Conclusion:
From the limited data available in this study, it may be recommended to screen for T.
gondii antibodies in HIV patients.
Publisher
Bentham Science Publishers Ltd.
Subject
Microbiology (medical),Pharmacology,Molecular Medicine,General Medicine