Current Methods Applied to Biomaterials – Characterization Approaches, Safety Assessment and Biological International Standards

Author:

Oliveira Justine P.R.1,Melendez-Ortiz H. Ivan2,Bucio Emilio3,Alves Patricia Terra4,Lima Mayara Ingrid Sousa5,Goulart Luiz Ricardo4,Mathor Monica B.1,Varca Gustavo H.C.1,Lugao Ademar B.1

Affiliation:

1. Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP, Sao Paulo – SP, Brazil

2. CONACyT – Centro de Investigacion en Quimica Aplicada, Saltillo, Mexico

3. Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad de Mexico, Mexico

4. Universidade Federal de Uberlandia, Instituto de Genetica e Bioquimica, Uberlandia - MG, Brazil

5. Universidade Federal do Maranhao, Departamento de Biologia, Sao Luis - MA, Brazil

Abstract

Safety and biocompatibility assessment of biomaterials are themes of constant concern as advanced materials enter the market as well as products manufactured by new techniques emerge. Within this context, this review provides an up-to-date approach on current methods for the characterization and safety assessment of biomaterials and biomedical devices from a physical-chemical to a biological perspective, including a description of the alternative methods in accordance with current and established international standards.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

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