Advances in Exosome Research in the Management of Lung Cancer-Reference-Cited by-同舟云学术

Advances in Exosome Research in the Management of Lung Cancer

Published:2023-04 Issue:10 Volume:23 Page:921-930
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Shen Huiqing¹,Cao Dawei¹,Zhang Xinri¹

Affiliation:

1. Department of Pulmonary and Critical Care Medicine, NHC Key Laboratory of Pneumoconiosis, Shanxi Key Laboratory of Respiratory Diseases, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

Abstract

Abstract: Lung cancer is one of the most common malignant tumors, and its death rate is much higher than that of colon, kidney, breast, and prostate cancers, and its 5-year survival rate is only 18%. Lung cancer has no specific clinical symptoms in its early stages and lacks effective detection, making early detection difficult. The survival rate for advanced lung cancer is meager, with a medi-an survival of only 12 months for stage IIIB/IV non-small cell lung cancer treated with platinum-based chemotherapy. Exosomes could provide vital information for the early diagnosis of lung can-cer and have the potential to become a tumor marker for lung cancer. In addition, scientists have proposed encouraging ways to treat lung cancer by loading drugs, proteins, microRNAs, and siR-NAs into exosomes. Therefore, studying lung cancer exosomes and exosomal nano drugs will pro-vide new ideas and approaches for the diagnosis and treatment of lung cancer. This paper reviews the progress of research on the biological functions of exosomes and exosomal nanomedicines and their applications in clinical practice.

Funder

Special Fund Project for Guiding Local Science and Technology Development by the Central Government

Chinese Academy of Medical Science

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference74 articles.

1. Postmus P.E.; Kerr K.M.; Oudkerk M.; Senan S.; Waller D.A.; Vansteenkiste J.; Escriu C.; Peters S.; Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2017,28(Suppl. 4),iv1-iv21

2. Vansteenkiste J.; Crinò L.; Dooms C.; Douillard J.Y.; Faivre-Finn C.; Lim E.; Rocco G.; Senan S.; Van Schil P.; Veronesi G.; Stahel R.; Peters S.; Felip E.; Stahel R.; Felip E.; Peters S.; Kerr K.; Besse B.; Vansteenkiste J.; Eberhardt W.; Edelman M.; Mok T.; O’Byrne K.; Novello S.; Bubendorf L.; Marchetti A.; Baas P.; Reck M.; Syrigos K.; Paz-Ares L.; Smit E.F.; Meldgaard P.; Adjei A.; Nicolson M.; Crinò L.; Van Schil P.; Senan S.; Faivre-Finn C.; Rocco G.; Veronesi G.; Douillard J-Y.; Lim E.; Dooms C.; Weder W.; De Ruysscher D.; Le Pechoux C.; De Leyn P.; Westeel V.; 2nd ESMO Consensus Conference on Lung Cancer: Early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up. Ann Oncol 2014,25(8),1462-1474

3. de Koning H.J.; van der Aalst C.M.; de Jong P.A.; Scholten E.T.; Nackaerts K.; Heuvelmans M.A.; Lammers J.W.J.; Weenink C.; Yousaf-Khan U.; Horeweg N.; van ’t Westeinde S.; Prokop M.; Mali W.P.; Mohamed Hoesein F.A.A.; van Ooijen P.M.A.; Aerts J.G.J.V.; den Bakker M.A.; Thunnissen E.; Verschakelen J.; Vliegenthart R.; Walter J.E.; ten Haaf K.; Groen H.J.M.; Oudkerk M.; Reduced lung-cancer mortality with volume ct screening in a randomized trial. N Engl J Med 2020,382(6),503-513

4. Aberle D.R.; Adams A.M.; Berg C.D.; Black W.C.; Clapp J.D.; Fagerstrom R.M.; Gareen I.F.; Gatsonis C.; Marcus P.M.; Sicks J.D.; Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011,365(5),395-409

5. Hong H.; Hahn S.; Matsuguma H.; Inoue M.; Shintani Y.; Honda O.; Izumi Y.; Asakura K.; Asamura H.; Isaka T.; Lee K.; Choi Y.S.; Kim Y.T.; Park C.M.; Goo J.M.; Yoon S.H.; Pleural recurrence after transthoracic needle lung biopsy in stage I lung cancer: a systematic review and individual patient-level meta-analysis. Thorax 2021,76(6),582-590

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