Affiliation:
1. Research Lab for Clinical & Translational Medicine, Hengyang Medical School, University of South China, Hengyang, 421001, China
Abstract
Abstract:As a circadian rhythm hormone, melatonin is widely present in the body and has rich physiological functions. Compared to its prominent circadian role, melatonin has been extensively studied in many fields as an ancient antioxidant. In addition to being considered a potent antioxi-dant, melatonin has also been found to play an important role in mitochondrial homeostasis. Mito-chondrial oxidative stress plays a crucial role in the occurrence and development of atherosclerosis. Therefore, the possible therapeutic value of melatonin as an antioxidant targeting mitochondria in atherosclerosis is worth exploring. The most widespread clinical applications of melatonin are in circadian rhythms and sleep, but the cardiovascular system may be the most promising area.
Funder
Natural Science Foundation of Hunan Province
Scientific Research Project of Hunan Provincial Department of Education
Innovative Training Program for College Students of Hunan Province
Postgraduate Research Innovation Project
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,General Medicine
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献