Biological Activities of Artemisinin Derivatives Beyond Malaria-Reference-Cited by-同舟云学术

Biological Activities of Artemisinin Derivatives Beyond Malaria

Published:2019-03-28 Issue:3 Volume:19 Page:205-222
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Liu Xiaoyan¹,Cao Jianguo²,Huang Guozheng²,Zhao Qingjie¹,Shen Jingshan¹

Affiliation:

1. CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

2. College of Life and Environmental Sciences, Shanghai Normal University, Shanghai, 201418, China

Abstract

Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene lactone structure. Because of its unique structural characteristics and promising anticancer, antivirus activities, it has recently received increasing attention. The aim of this review is to summarize recent discoveries of artemisinin's novel derivatives with new pharmaceutical effects beyond malaria with a focus on its antitumor and antivirus activity, as well as potential results of combination therapy with other clinical drugs.

Funder

Strategic Priority Research Program of the Chinese Academy of Sciences

Institutes for Drug Discovery and Development, Chinese Academy of Sciences

Shanghai Pujiang Program

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference156 articles.

1. Efferth T, Li PCH, Konkimalla VSB, Kaina B. From traditional chinese medicine to rational cancer therapy.

2. Lü S, Wang Q, Li G, Sun S, Guo Y, Kuang H. The treatment of rheumatoid arthritis using chinese medicinal plants: From pharmacology to potential molecular mechanisms.

3. Ding W, Gu J, Cao L, Li N, Ding G, Wang Z, Chen L, Xu X, Xiao W. Traditional chinese herbs as chemical resource library for drug discovery of anti-infective and anti-inflammatory.