Marine Actinomycetes-derived Natural Products-Reference-Cited by-同舟云学术

Marine Actinomycetes-derived Natural Products

Published:2020-01-03 Issue:31 Volume:19 Page:2868-2918
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Yang Chengfang¹,Qian Rui¹,Xu Yao¹,Yi Junxi¹,Gu Yiwen¹,Liu Xiaoyu¹,Yu Haobing¹,Jiao Binghua¹,Lu Xiaoling¹,Zhang Wei²

Affiliation:

1. College of Basic Medical Sciences, Department of Biochemistry and Molecular Biology, Second Military Medical University, Shanghai, China

2. Centre for Marine Bioproducts Development, Flinders University, Adelaide, Australia

Abstract

: Actinomycetes is an abundant resource for discovering a large number of lead compounds, which play an important role in microbial drug discovery. Compared to terrestrial microorganisms, marine actinomycetes have unique metabolic pathways because of their special living environment, which has the potential to produce a variety of bioactive substances. In this paper, secondary metabolites isolated from marine actinomycetes are reviewed (2013-2018), most of which exhibited cytotoxic, antibacterial, and antiviral biological activities.

Funder

National Key R&D Program of China

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

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