Progress in Studies on Structural and Remedial Aspects of Newly Born Coronavirus, SARS-CoV-2-Reference-Cited by-同舟云学术

Progress in Studies on Structural and Remedial Aspects of Newly Born Coronavirus, SARS-CoV-2

Published:2020-11-03 Issue:26 Volume:20 Page:2362-2378
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Gupta Satya P.¹

Affiliation:

1. Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut-250005, India

Abstract

The article highlights an up-to-date progress in studies on structural and the remedial aspects of novel coronavirus 2019-nCoV, renamed as SARS-CoV-2, leading to the disease COVID-19, a pandemic. In general, all CoVs including SARS-CoV-2 are spherical positive single-stranded RNA viruses containing spike (S) protein, envelope (E) protein, nucleocapsid (N) protein, and membrane (M) protein, where S protein has a Receptor-binding Domain (RBD) that mediates the binding to host cell receptor, Angiotensin Converting Enzyme 2 (ACE2). The article details the repurposing of some drugs to be tried for COVID-19 and presents the status of vaccine development so far. Besides drugs and vaccines, the role of Convalescent Plasma (CP) therapy to treat COVID-19 is also discussed.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,General Medicine

Reference110 articles.

1. Woo P.C.; Huang Y.; Lau S.K.; Yuen K.Y.; Coronavirus genomics and bioinformatics analysis. Viruses 2010,2(8),1804-1820

2. Woo P.C.; Lau S.K.; Lam C.S.; Lau C.C.; Tsang A.K.; Lau J.H.; Bai R.; Teng J.L.; Tsang C.C.; Wang M.; Zheng B.J.; Chan K.H.; Yuen K.Y.; Discovery of seven novel mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J Virol 2012,86(7),3995-4008

3. Ashour H.M.; Elkhatib W.F.; Rahman M.M.; Elshabrawy H.A.; Elshabrawy H.A.; Insights into the recent 2019 novel coronavirus (SARS- CoV-2) in light of past human coronavirus outbreaks. Pathogens 2020,9(3),186

4. Drosten C.; Günther S.; Preiser W.; van der Werf S.; Brodt H.R.; Becker S.; Rabenau H.; Panning M.; Kolesnikova L.; Fouchier R.A.; Berger A.; Burguière A.M.; Cinatl J.; Eickmann M.; Escriou N.; Grywna K.; Kramme S.; Manuguerra J.C.; Müller S.; Rickerts V.; Stürmer M.; Vieth S.; Klenk H.D.; Osterhaus A.D.; Schmitz H.; Doerr H.W.; Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003,348(20),1967-1976

5. Zaki A.M.; van Boheemen S.; Bestebroer T.M.; Osterhaus A.D.; Fouchier R.A.; Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012,367(19),1814-1820

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