1. Department of Chemical Sciences, University of Naples Federico II, 80126 Naples, Italy
2. Department of Biology, University of Naples Federico II, 80126 Naples, Italy
3. Machine Biology Group, Departments of Psychiatry and Microbiology, Institute for Biomedical Informatics, Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, and Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States