Inhibition of Butyrylcholinesterase with Fluorobenzylcymserine, An Experimental Alzheimer's Drug Candidate: Validation of Enzoinformatics Results by Classical and Innovative Enzyme Kinetic Analyses

Author:

Kamal Mohammad A.1,Shakil Shazi2,Nawaz Muhammad S.3,Yu Qian-sheng4,Tweedie David5,Tan Y.6,Qu Xianqin6,Greig Nigel H.7

Affiliation:

1. King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia

2. Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia

3. Department of Biological Science, COMSATS, Islamabad, Pakistan; 4Novel Global Community Educational Foundation, New South Wales, Australia

4. Drug Design & Development Section, Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, United States

5. Drug Design & Development Section, Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, United States

6. Department of Medical & Molecular Biosciences, Faculty of Science, University of Technology, Sydney, NSW, Australia

7. Drug Design & Development Section, Gerontology Research Center, Room 4B02, 5600 Nathan Shock Dr., Baltimore, MD 21224, United States

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,General Neuroscience

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