Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications-Reference-Cited by-同舟云学术

Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications

Published:2024-04 Issue:10 Volume:24 Page:869-884
ISSN:1568-0266
Container-title:Current Topics in Medicinal Chemistry
language:en
Short-container-title:CTMC

Author:

Wu Lei¹,Bai Lin¹,Dai Wenshu²,Wu Yaping¹,Xi Pengjun³,Zhang Jie¹,Zheng Lily⁴⁵

Affiliation:

1. Core Facility of West China Hospital, Sichuan University, Chengdu, 610041, China

2. NHC Key Laboratory of Transplant Engineering and Immunology, Frontier Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China

3. Division of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden

4. TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, Sichuan Province, China

5. Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu 610041, China

Abstract

Background: Traditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer. Objective: This work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.

Funder

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Publisher

Bentham Science Publishers Ltd.

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