Affiliation:
1. Department of Pharmaceutical Technology, University College of Engineering, Anna University BIT Campus, Tiruchirappalli,
Tamil Nadu, India
2. Department of Pharmaceutics, S. A. Raja Pharmacy College, Vadakangulam Tirunelveli,
Tamil Nadu, India
Abstract
Abstract:
In recent decades, increased demand for food has been caused by a rapid rise in the human
population, which triggers agricultural intensification. To resist undesired pests from infecting crops,
farmers widely utilize pesticides to improve agricultural production during the pre-harvest period. Despite
the fact that pesticides cause a number of health risks, there is insufficient monitoring of these toxins.
Therefore, it is important to develop a specific, accurate, and efficient method for determining the pesticides
in varied samples in order to safeguard health against potential risks. Due to the lower concentrations
of active compounds and their diversity of availability, it is challenging to detect pesticide residues
in different samples. In this case, to effectively separate, identify, and accurately quantify pesticides at
low concentrations in a variety of samples, a reliable analytical methodology is needed. Recently, the
application of high-performance thin layer chromatography (HPTLC) offers a wider scope with excellent
separation, identification, and quantitative/qualitative determination in pesticide analysis. In spite of their
extremely low quantities, pesticide residues can be accurately and precisely identified using HPTLC.
HPTLC has a number of benefits, such as easy sample preparation, automation, densitometry, and hyphenation,
and is particularly well suited for identification and detection. Concerning this, the proposed
review paper provides an overview of stationary phases, mobile phases, sample applicators, visualization,
derivatization, and detection of HPTLC utilized for the identification and detection of pesticide residues
in agriculture and environmental samples.
Publisher
Bentham Science Publishers Ltd.