Affiliation:
1. Department of Chemical Engineering, Monash University, Clayton, Victoria 3800, Australia
2. Faculty of Engineering, Monash Institute of Medical Engineering (MIME), Monash University, Clayton, Victoria 3800, Australia
Abstract
Background:
Soft wearable electrochemical biosensors are increasing attention over the past several years due to their potential for non-invasive personalized health monitoring in real-time and in-situ.
Objective:
Herein, we cover the design, fabrication, and applications of soft electrochemical sensing systems. Firstly, we describe key design requirements for fabricating the mechanically compliant electrochemical biosensors. This is followed by a description of typical sensor configurations and the detecting methodologies. Next, on-body soft electrochemical biosensing and cell/tissue-based “wearable” sensing applications are summarized. Detection of key biochemical markers, including metabolites (glucose, lactate, uric acid, and ethanol), electrolytes (Na+ and K+), nutrients (vitamin C), hormones (cortisol), and proteins (TNF-α), as well as cellular signalling molecules (nitric oxide, hydrogen peroxide and serotonin), are the focus of the discussion in this review.
Conclusion:
We conclude the review with discussions on future opportunities and challenges of the soft and wearable electrochemical biosensors.
Publisher
Bentham Science Publishers Ltd.
Cited by
8 articles.
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