Aptamer Based Diagnosis: A Cost-Effective and Suitable Point of Care Testing Method Against SARS Coronavirus-2 (SARs-CoV-2) and Other Rapidly Spreading Diseases-Reference-Cited by-同舟云学术

Aptamer Based Diagnosis: A Cost-Effective and Suitable Point of Care Testing Method Against SARS Coronavirus-2 (SARs-CoV-2) and Other Rapidly Spreading Diseases

Published:2021-05-20 Issue:1 Volume:10 Page:3-6
ISSN:2211-5501
Container-title:Current Biotechnology
language:en
Short-container-title:CBIOT

Author:

Kumar Vivek¹^ORCID,Yadav Gulab S.²,Banerjee Basu D.³^ORCID

Affiliation:

1. Department of Biotechnology, IMS Engineering College, Ghaziabad, Uttar Pradesh-201009, Dr. A.P.J. Abdul Kalam Techincal University, Lucknow, Uttar Pradesh-226031, India

2. Department of Biotechnology, Maharaja Agrasen University, Solan, Himachal Pradesh-174103, India

3. Faculty of Medical Sciences, Department of Biochemistry, University College of Medical Sciences & Guru Tegh Bahadur Hospital, University of Delhi, Dilshad Garden, Delhi, India

Abstract

The current SARS coronavirus-2 (SARS-CoV-2) pandemic has raised serious concerns regarding the inefficiency of available diagnostic methods for rapid and efficient detection of the disease. It is agreed widely that Real-time Polymerase Chain Reaction (RT-PCR) and antibody- based assays have several limitations that did not help much in preventing the exponential spread of the disease in a short span of period. Unarguably, the world needs “new-generation diagnostic intervention(s)” against rapidly spreading disease like SARS-CoV-2. We have presented an aptamer-based strategy as a possible point of care testing for the diagnosis of the disease. It has several advantages over current tools available and can be used for efficient combating by the mean of quick,cost-effective and much more accurate diagnostic against the enigmatic SARS-CoV-2 disease and similar pandemic which world may possibly encounter in the future.

Publisher

Bentham Science Publishers Ltd.

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference23 articles.

1. Loeffelholz M.J.; Tang Y.W.; Laboratory diagnosis of emerging human coronavirus infections - the state of the art. Emerg Microbes Infect 2020,9(1),747-756

2. Li Z.; Yi Y.; Luo X.; Xiong N.; Liu Y.; Li S.; Sun R.; Wang Y.; Hu B.; Chen W.; Zhang Y.; Wang J.; Huang B.; Lin Y.; Yang J.; Cai W.; Wang X.; Cheng J.; Chen Z.; Sun K.; Pan W.; Zhan Z.; Chen L.; Ye F.; Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis. J Med Virol 2020,92(9),1518-1524

3. Xiao A.T.; Tong Y.X.; Zhang S.; False negative of RT-PCR and prolonged nucleic acid conversion in COVID-19: Rather than recurrence. J Med Virol 2020,92(10),1755-1756

4. Zu Z.Y.; Jiang M.D.; Xu P.P.; Chen W.; Ni Q.Q.; Lu G.M.; Zhang L.J.; Coronavirus Disease 2019 (COVID-19): A Perspective from China. Radiology 2020,296(2),E15-E25

5. Udugama B.; Kadhiresan P.; Kozlowski H.N.; Malekjahani A.; Osborne M.; Li V.Y.C.; Chen H.; Mubareka S.; Gubbay J.B.; Chan W.C.W.; Diagnosing COVID-19: The Disease and Tools for Detection. ACS Nano 2020,14(4),3822-3835