Author:
Silva Luciano B.,dos Santos Neto Alexandrino P.,Maia Sandra M.A.S.,dos Santos Guimarães Carolina,Quidute Iliana L.,Carvalho Alessandra de A.T.,Júnior Severino A.,Leão Jair C.
Abstract
TNF-α is a member of the vast cytokine family being considered a proinflammatory substance produced many by macrophages and other cells belonging to the innate immunity, many of them classified as indeed Antigen Presenting Cells (APCs) involved in the complex chemotactic process of activation of the adaptive immunity. The aim of this work was to accomplish a literature review concerning the main pathologies that have TNF-α as a modulating agent in other to bring light to the main interactions present in the inflammation installed.
Publisher
Bentham Science Publishers Ltd.
Cited by
27 articles.
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