Affiliation:
1. SRM Modinagar College of Pharmacy, SRM Institute of Science and Technology, Delhi NCR Campus, Modinagar, Ghaziabad
2. KIET School of Pharmacy, KIET Group of Institutions, Ghaziabad
3. School of Pharmacy, Bharat Institute of Technology, Meerut
4. Sunder Deep Pharmacy College, Dasna, Ghaziabad
Abstract
Abstract:
Cancer and other diseases can be treated with cubosomes, which are lyotropic nonlamellar
liquid crystalline nanoparticles (LCNs). These cubosomes can potentially be a highly
versatile carrier with theranostic efficacy, as they can be ingested, applied topically, or injected
intravenously. Recent years have seen substantial progress in the synthesis, characterization,
regulation of drug release patterns, and target selectivity of loaded anticancer bioactive compounds.
However, its use in clinical settings has been slow and necessitates additional proof.
Recent progress and roadblocks in using cubosomes as a nanotechnological intervention against
various cancers are highlighted. In the last few decades, advances in biomedical nanotechnology
have allowed for the development of "smart" drug delivery devices that can adapt to external
stimuli. By improving therapeutic targeting efficacy and lowering the negative effects of payloads,
these well-defined nanoplatforms can potentially promote patient compliance in response
to specific stimuli. Liposomes and niosomes, two other well-known vesicular systems, share a
lipid basis with cubosomes. Possible applications include a novel medication delivery system for
hydrophilic, lipophilic, and amphiphilic drugs. We evaluate the literature on cubosomes, emphasizing
their potential use in tumor-targeted drug delivery applications and critiquing existing
explanations for cubosome self-assembly, composition, and production. As cubosome dispersion
has bioadhesive and compatible features, numerous drug delivery applications, including oral,
ocular, and transdermal, are also discussed in this review.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biotechnology
Cited by
1 articles.
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