Affiliation:
1. Department of Interventional Radiology,
Shenzhen People’s Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital,
Southern University of Science and Technology), Shenzhen, China
2. The Second Clinical Medical College, Jinan University, Shenzhen, China
Abstract
Objective:
The aim of this study was to evaluate the clinical value of computed tomography-guided localization needle (LN) and methylene blue (MB) for pulmonary nodule localization.
Materials and Methods:
Between November 2019 and January 2022, 547 patients underwent computed tomography-guided LN (n=171) or MB (n=376) localization and video-assisted thoracoscopic surgery (VATS) resection.
Results:
In total, 171 and 376 nodules were localized via LN and MB, respectively, with respective
technical localization success rates of 92.98 % and 88.56 % (p = 0.111). The pulmonary nodule localization
time was significantly shorter for the MB group than for the LN group (p < 0.05). However, the
rates of total complication, chest pain, and cough were significantly lower in the LN group (χ2 =
8.251/25.092/5.127, all p < 0.05). Furthermore, the LN group had a shorter VATS time than the MB
group (p < 0.05). The VATS achieved a 100% operation success rate in both groups, and there was no
significance between groups with respect to the types of surgery (p > 0.05) or the blood loss (p >
0.05). Moreover, logistic regression analysis showed that the localization technique was an independent
risk factor for total complications and chest pain.
Conclusion:
Both techniques can effectively localize pulmonary nodules before VATS. MB had a shorter localization time, but the LN had a shorter VATS time and a lower incidence of complications, especially chest pain.
Publisher
Bentham Science Publishers Ltd.
Subject
Radiology, Nuclear Medicine and imaging