FDG-PET/CT Assessment of Pulmonary Sarcoidosis: A Guide for Internists

Author:

Tana Marco1,di Carlo Silvio2,Romano Marcello3,Alessandri Massimo4,Schiavone Cosima5,Montagnani Andrea1

Affiliation:

1. Internal Medicine Unit, USL Sudest Toscana, Grosseto, Italy

2. Geriatrics Clinic, AUSL Pescara, Pescara, Italy

3. Geriatric Unit, Garibaldi Hospital, Catania, Italy

4. Internal Medicine Unit, USL 7 Siena, Toscana, Italy

5. Department of Internistic Ultrasound, G. D'Annunzio University, Chieti, Italy

Abstract

Background:18F-fluorodeoxyglucose positron emission tomography integrated with computed tomography (18-F-FDG-PET/CT) is getting wide consensus in the diagnosis and staging of neoplastic disorders and represents a useful tool in the assessment of various inflammatory conditions. </P><P> Discussion: Sarcoidosis is an uncommon disease characterized by the systemic formation of noncaseating granulomas. Lungs are the sites most often affected, and investigation with high resolution computed tomography and biopsy is essential to achieve a correct diagnosis. 18-F-FDGPET/ CT is effective in the assessment of pulmonary sarcoidosis by demonstrating pulmonary and extrathoracic involvement and findings correlate well with pulmonary function in patients affected.Conclusion:This review would illustrate the usefulness and limits of 18-F-FDG-PET/CT in the assessment of pulmonary sarcoidosis.

Publisher

Bentham Science Publishers Ltd.

Subject

Radiology, Nuclear Medicine and imaging

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