Microsponges: A Neoteric Approach for the Effective Management of Osteoarthritis

Abstract

Background: A microsponge delivery system (MDS) is a cutting-edge and distinctive method of structured medication delivery. Regulated drug distribution is now possible with the use of microsponge technology. Techniques for drug release are created specifically to distribute medi-cations to the body's various locations. As a result, pharmacological therapy becomes more effec-tive, and patient compliance significantly affects the health care system. Main Body: MDS consists of porous microspheres with a substantially porous structure and a very small spherical shape, ranging in size from 5 to 300 microns. MDS is typically used to administer medications through topical channels, but new research has demonstrated the promise of this tech-nique for parenteral, oral, and ocular drug delivery. Topical formulations are an attempt to manage diseases like osteoarthritis, rheumatoid arthritis, psoriasis, etc. While reducing the drug's side ef-fects, MDS can readily change the pharmaceutical release shape and enhance formulation stability. Reaching the highest peak plasma concentration in the blood is the main goal of microsponge medi-cation delivery. The ability of MDS to self-sterilize is by far the most notable quality. Conclusion: In countless studies, MDS is employed as an anti-allergic, anti-mutagenic, and non-irritant. This review covers the overview of microsponges along with their release mechanism. The article focuses on the marketed formulation of microsponges and patent data of the same. This re-view will be helpful for researchers working in MDS technology.