A Mini-Review: The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells and Relevant Signaling Cascades-Reference-Cited by-同舟云学术

A Mini-Review: The Therapeutic Potential of Bone Marrow Mesenchymal Stem Cells and Relevant Signaling Cascades

Published:2019-04-29 Issue:3 Volume:14 Page:214-218
ISSN:1574-888X
Container-title:Current Stem Cell Research & Therapy
language:en
Short-container-title:CSCR

Author:

Yang Wen¹,Ma Bo¹

Affiliation:

1. Department of Ophthalmology, Xi'an Fourth Hospital, Xi'an Shaanxi, 710000, China

Abstract

Bone marrow mesenchymal stem cells (BMSCs) characterized multi-directional differentiation, low immunogenicity and high portability, serve as ideal “seed cells” in ophthalmological disease therapy. Therefore, in this mini-review, we examined the recent literature concerning the potential application of BMSCs for the treatment of ophthalmological disease, that includes: the cellular activity of BMSCs transplantation, migration and homing, as well as the immuno-modulatory and antiinflammatory effects of BMSCs and signaling involved. Each aspect is complementary to the others and together these aspects promoted further understanding of the potential use of BMSCs in treating ophthalmological diseases.

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine,Medicine (miscellaneous)

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