Gli1+ Mesenchymal Stem Cells in Bone and Teeth-Reference-Cited by-同舟云学术

Gli1+ Mesenchymal Stem Cells in Bone and Teeth

Published:2022-08 Issue:6 Volume:17 Page:494-502
ISSN:1574-888X
Container-title:Current Stem Cell Research & Therapy
language:en
Short-container-title:CSCR

Author:

Wu Yange¹^ORCID,Zhou Xueman²,Yuan Wenxiu²,Liu Jiaqi²,Yang Wenke²,Zhu Yufan²,Ye Chengxinyue²,Xiong Xin²,Zhang Qinlanhui²,Liu Jin³,Wang Jun²^ORCID

Affiliation:

1. Department of Orthodontics, State Key Laboratory of Oral Disease, National Clinical Research Center for Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China

2. Department of Orthodontics, State Key Laboratory of Oral Disease, National Clinical Research Center for Oral Disease, West China Hospital of Stomatology, Sichuan University, Chengdu, China

3. Lab for Aging Research, National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

Abstract

Abstract: Mesenchymal stem cells (MSCs) are remarkable and noteworthy. Identification of markers for MSCs enables the study of their niche in vivo. It has been identified that glioma-associated oncogene 1 positive (Gli1+) cells are mesenchymal stem cells supporting homeostasis and injury repair, especially in the skeletal system and teeth. This review outlines the role of Gli1+ cells as an MSC subpopulation in both bones and teeth, suggesting the prospects of Gli1+ cells in stem cell- based tissue engineering.

Funder

National Natural Science Foundation of China

Science and Technology Department of Sichuan Province

Chengdu Science and Technology Program

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine,Medicine (miscellaneous)

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