Stem cells treatment for wilson disease-Reference-Cited by-同舟云学术

Stem cells treatment for wilson disease

Published:2021-10-06 Issue: Volume:16 Page:
ISSN:1574-888X
Container-title:Current Stem Cell Research & Therapy
language:en
Short-container-title:CSCR

Author:

Tang Shan¹,Bai Li²,Duan Zhongping²,zheng Sujun¹

Affiliation:

1. The First Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, China

2. The Fourth Unit, Department of Hepatology, Beijing YouAn Hospital, Capital Medical University, Beijing, China

Abstract

: Wilson disease (WD) is a copper excretion disorder, mainly caused by mutations in the ATP7B gene. Pharmacological therapies and liver transplantation are currently the main treatment methods for WD, but they face problems such as drug treatment compliance, adverse reactions, and shortage of liver donors. Stem cell therapy of WD may correct abnormal copper metabolism permanently, which is the focus of current research. In this review, we summarized the latest research on stem cells treatment for WD, as well as current challenges and future expectations.

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine,Medicine (miscellaneous)

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