Uncaria Tomentosa (Willd. ex Schult.): Focus on Nutraceutical Aspects

Author:

Nazhand Amirhossein1,Durazzo Alessandra2,Lucarini Massimo2,Silva Amelia M.3,Souto Selma B.4,Severino Patricia5,Souto Eliana B.6,Santini Antonello7

Affiliation:

1. Department of Biotechnology, Sari Agricultural Science and Natural Resource University, Sari 48181 68984, 9th km of Farah Abad Road, Mazandaran, Iran

2. CREA-Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Roma, Italy

3. School of Biology and Environment, University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, P-5001-801 Vila Real, Portugal

4. Department of Endocrinology, Hospital de São João, , Alameda Prof. Hernâni Monteiro, 4200–319 Porto, Portugal

5. University of Tiradentes (UNIT), Industrial Biotechnology Program, Av. Murilo Dantas 300, 49032-490 Aracaju, Brazil

6. Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal

7. Department of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy

Abstract

: Medicinal plants have been globally exploiting as an alternative to chemical drugs in the treatment of several diseases due to low unwanted side effects, environmentally friendly nature, and low production costs. Therefore, it is important to analyze the therapeutic properties of various medicinal plants to understand their potential bioactivity. Uncaria tomentosa is one of these medicinal plants with many health-promoting effects. Although the geographical resources of cat's claw go back to the remote tropics of the Amazon, industrialized countries use the plant extensively in trade. Various parts of the plants such as flowers, leaves, Stem, hooks, and seeds are mainly used medicinally to treat inflammation, asthma, allergies, skin impurities, microbial infections, neurodegenerative diseases, cancer, cirrhosis, gastrointestinal disorders, arthritis, heart disease, rheumatism, and fever. The endpoint of this review article is to prospectively scrutinize in vitro and in vivo the therapeutic potential of this plant, especially in terms of its nutritional applications and healthbeneficial effects.

Publisher

Bentham Science Publishers Ltd.

Subject

General Pharmacology, Toxicology and Pharmaceutics

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