Recent Patents and Potential Applications of Homogenisation Techniques in Drug Delivery Systems

Abstract

Background: The term homogenize means "to force or provide coalesce." Homogenisation is a process to attain homogenous particle size. The objective of homogenisation process is to use fluid force to split the fragments or tiny particles contained in the fluids into minimal dimen-sions and form a sustainable dispersion suitable for further production. Results: The present study focus on the use of the homogenisation in drug delivery system. Homogenisation process aims to achieve the particle size in micro-and nano- range as it affects the different parameters in the formulation and biopharmaceutical profile of the drug. Particle size reduction plays a crucial role in influencing drug dissolution and absorption. The reduced particle size enhances the stability and therapeutic efficacy of the drug. Homogenisa-tion technology ensures to achieve effective, clinically efficient, and targeted drug delivery with minimal side effects Conclusion: Homogenization technology is an efficient and easy method of size reduction to increase solubility, bioavailability, and stability of drug carriers. This article gives an overview of the process attributes affecting the homogenisation process, the patenting of homogeniser types, design, the geometry of valves and nozzles, and its role in drug delivery.