Affiliation:
1. College of Pharmacy, Pt. B.D. Sharma University of Health Sciences, Rohtak, India
Abstract
Background::
Breast cancer is the most prevalent cancer among women. About 685K deaths
were globally listed in 2020 by the World Health Organization. Nowadays, scientists prefer to use herbal
medicines due to their low toxicity. Herbal medicines are used to overcome the toxicity effects of
surgical removal, radio-chemo therapy and medication, which have a lot of risk of damaging the healthy
tissues. To overcome this, enhance bioavailability and target specify, nano-formulation chemotherapy
was introduced using herbal moiety for anticancer activity. The use of metallic nanoparticles (MNPs),
particularly those made of silver, cobalt, zinc, and gold as contrast, antibacterial, anticancer, and drug
delivery agents has revolutionised the medicinal field. Although MNPs can be made via exacting physical
and chemical processes, a biological method utilising natural materials has been established recently.
Objectives::
This review article will offer a succinct explanation of the use of MNPs and its potential
impact on herbal medicines in the future.
Methods:
Using PRISMA principles, this review systematically examines studies that concentrate on metal nanoparticles loaded with herbal compounds for the treatment of breast cancer. Various Databases were studied: PubMed, Elsevier, ScienceDirect, SpringerLink, Taylor & Francis Online, ACS Publications, Publishing Royal Society of Chemistry, and Future Medicines. Studies were selected if they were peer-reviewed primary studies published in the past 10 years.
Results:
We found that many herbal nano-formulations are more effective in breast cancer treatment than other types of formulations. Efficacy, safety and drug stability are also enhanced using nano-formulations.
Conclusion:
Nano-formulation is found to be more effective in the treatment of breast cancer.
Publisher
Bentham Science Publishers Ltd.
Subject
General Engineering,Condensed Matter Physics,General Materials Science
Cited by
2 articles.
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