A Comprehensive Review on COVID-19: Emphasis on Current Vaccination and Nanotechnology Aspects

Author:

Dewangan Hitesh Kumar1,Rai Akriti2,Shah Kamal3,Sharma Rajiv1ORCID

Affiliation:

1. University Institute of Pharma Sciences (UIPS), Chandigarh University NH-95, Chandigarh Ludhiana Highway, Mohali Punjab, India

2. Ashoka Institute of Technology and Management, Ashoka Engineering Chauraha, Paharia Sarnath Road, Sarnath, Varanasi, Uttar Pradesh, India

3. Institute of Pharmaceutical Research (IPR), GLA University, Mathura, NH-2, Mathura Delhi Road, Chaumuhan Mathura, Uttar Pradesh, India

Abstract

Abstract: COVID-19, caused by the SARS-CoV-2 virus, has been expanding. SARS-CoV caused an outbreak in early 2000, while MERS-CoV had a similar expansion of illness in early 2010. Nanotechnology has been employed for nasal delivery of drugs to conquer a variety of challenges that emerge during mucosal administration. The role of nanotechnology is highly relevant to counter this “virus” nano enemy. This technique directs the safe and effective distribution of accessible therapeutic choices using tailored nanocarriers, as well as the interruption of virion assembly, by preventing the early contact of viral spike glycoprotein with host cell surface receptors. This study summarises what we know about earlier SARS-CoV and MERS-CoV illnesses, with the goal of better understanding the recently discovered SARS-CoV-2 virus. It also explains the progress made so far in creating COVID-19 vaccines/ treatments using existing methods. Furthermore, we studied nanotechnology- based vaccinations and therapeutic medications that are now undergoing clinical trials and other alternatives.

Publisher

Bentham Science Publishers Ltd.

Subject

General Engineering,Condensed Matter Physics,General Materials Science

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Emerging Trends on Nanovaccine Administration and Functionalization Strategies for Immunization;Journal of Computational Biophysics and Chemistry;2024-04-05

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